Targeting Three Brain Regions (Bilateral SMA, Left & Right DLPFC) Sequentially in One Session Using Combined rTMS and iTBS in Treatment-Refractory OCD: A Case Report

SOURCE: Clinical Psychopharmacology and Neuroscience. 20(4) (pp 773-776), 2022.

DATE OF PUBLICATION: 2022.

AUTHOR: Chou P.-H.; Sack A.T.; Su K.-P.

ABSTRACT: Repetitive transcranial magnetic stimulation (rTMS) has been widely used as a therapy for refractory obsessive-compulsive disorder (OCD). However, it remains unclear which exact target and stimulation sequence of rTMS is most effective for OCD. Here, we report the case of an 18-year-old female with treatment-refractory OCD whose symptoms markedly improved after combined rTMS and intermittent theta-burst stimulation over the bilateral dorsolateral prefrontal cortex and supplementary motor area. Our report indicates that combining treatment sequences that stimulate different brain regions sequentially is feasible and may clinically benefit patients suffering from OCD.

FULL ARTICLE LINK: https://www.cpn.or.kr/journal/view.html?doi=10.9758/cpn.2022.20.4.77