Transcranial Direct Current Stimulation for Treatment-Resistant Obsessive-Compulsive Disorder-A Large Case Series

SOURCE: Asian Journal of Psychiatry. 60:102625, 2021 Jun.

AUTHORS: Thamby A; Seshachala K; Sharma L; Thimmashetty VH; Balachander S; Shivakumar V; Hazari N; Chhabra H; Arumugham SS; Ts J; K M; Venkatasubramanian G; Reddy YCJ; Narayanaswamy JC

OBJECTIVE: The present study is a large case series evaluating the benefits of transcranial direct current stimulation (tDCS) in treatment-resistant obsessive compulsive disorder (OCD).

METHODS: We reviewed the charts of 32 patients with treatment-resistant OCD who received 10-20 sessions of anodal pre-SMA tDCS.

RESULTS: Overall, 9 (28 %) showed at least partial response to tDCS at the end of 10-20 sessions [responders = 8 (25 %), partial responders = 1 (3%)]. Two out of three partial responders at the end of 10 sessions had response at the end of 20 sessions.

CONCLUSIONS: tDCS may benefit a proportion of patients with treatment-resistant OCD.